2023 Experiential Internship - Molecular Profiling and Drug Delivery:Biopharmaceutics (Illinois)

2023 Experiential Internship - Molecular Profiling and Drug Delivery:Biopharmaceutics (Illinois)

Abbvie | Hunstville, TX, 77340, US
Salary Range:$34,000 – $41,000 Salary range estimated by Zippia

Posted a month ago

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Description

ABOUT ABBVIE

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.

For more information about AbbVie, please visit us at www.abbvie.com.

Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.

MOLECULAR PROFILING AND DRUG DELIVERY: BIOPHARMACEUTICS INTERNSHIP OVERVIEW

Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie’s Experiential Interns.

AbbVie’s Biopharmaceutics team, within the Molecular Profiling and Drug Delivery (MPDD) function, is seeking an intern to assist in the development and applications of Physiologically based biopharmaceutics models (PBBM). This work will support the selection and biopharmaceutic understanding of novel drug candidates. The intern will have the opportunity to build and utilize absorption models to support the selection of small molecule clinical candidates, solid form, and clinical formulation strategies for oral delivery. In this exciting opportunity the intern will be able to grow and pursue new opportunities with in silico and in vitro approaches to predict the performance of oral formulations.

KEY RESPONSIBILITIES INCLUDE:

  • Evaluate the use of in silico, in vitro, and in vivo pre-clinical data to build PBBM models that impact our biopharmaceutic understanding of drug candidates
  • Routinely use and develop advanced biopharmaceutics models and simulations, including gastrointestinal transit models in GastroPlus, Simcyp or Matlab

  • Apply biopharmaceutics, physical chemistry, and chemical engineering principles to guide candidate selection and the development of drug substance and drug product strategies

  • Demonstrate excellent communication skills and specifically illustrate strong oral and written technical communications
  • MINIMUM QUALIFICATIONS

  • Currently enrolled in university, pursuing a Master’s or PhD degree, in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Chemical Engineering or related field

  • Must be enrolled in university during the internship period

  • PREFERRED QUALIFICATIONS

  • Fundamental understanding of physicochemical properties as related to formulation design
  • Working knowledge of physiological barriers to drug absorption, including various potential transport mechanisms

  • Experience in the development of in vitro approaches towards understanding in vivo performance

  • Experience with analytical approaches toward physicochemical characterization of small-molecule candidates (i.e. HPLC, DSC, TGA, PXRD, drug release)
  • Working knowledge of typical formulation approaches and drug delivery strategies
  • Familiarity with PBBM/PBPK software platforms utilized for oral absorption modeling
  • BENEFITS AND AMENITIES

  • Competitive pay
  • Opportunity to connect with Abbvie leaders and scientists.

  • Exposure to state-of-the-art facilities and experts in drug product development

  • EQUAL EMPLOYMENT OPPORTUNITY

    At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.