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Lead Research Scientist - Mammalian Cell Biology

I am working with a great start-up conducting exciting and ground-breaking research focusing on developing therapies to address the diseases and disabilities of ageing. Having just received significant funding to further investigate the concept, the company are now looking for a skilled and experienced Lead Research Scientist Mammalian Cell Culture to support the existing team and lead the hands-on scientific research at the Babraham Science Campus in Cambridge.

Youll be hands-on from day one at the start of an exciting company with bags of potential and will be able to participate in the structure and trajectory of the company and its project in an environment that encourages everyone to have a voice and invest in the success of the project and influence its scientific and business development growth.

The ideal candidate will be a naturally curious scientist who can work autonomously, identifying priorities and objectives and possesses the self-discipline to relentlessly pursue solutions and find the shortest, most efficient and cost-effective way to answer important scientific questions. Youll be able to demonstrate a strong background in setting up programs and solving problems all the while keeping close attention to deadlines, milestones and budgets. As one of the scientific leaders in the business you will help recruit and then lead a small group developing assays of cell function and ageing, testing FAB's molecules, and dissecting mechanisms of action at protein and transcriptional levels and be central in the publication of the work at conferences and in scientific papers.

This is a key leadership role in a flexible, fast growning startup in a significant and exciting area of therapeutic discovery and would be ideal for scientists who wish to develop the leadership in a commercial context without moving away from the hands on science.

Your experience and skills (essential for the role):

Relevant PhD and Post-doctoral experience in an academic or commercial setting

Experience in long-term culture of primary mammalian cells in both 'simple' and matrix-supported systems, ideally human cells

Experience in deploying assays of cell differentiation, apoptosis or senescence, at either protein or transcriptional levels

Excellent communication skills and a track record of working effectively in diverse teams

Ability to self-start, work independently, set own goals and priorities

Any of the following skills will help your application standout (desirable skills)

Experience in monitoring and assaying cell differentiation, especially in keratinocytes, muscle stem cells or immune cells

Experience in assays to distinguish cell fates (senescence, apoptosis, pyroptosis etc)

Knowledge of in vitro wound healing models, including scratch models and gel contraction

Experience in using quantitative and semi-quantitative ELISAs for measuring protein levels in cultured cells

Experience in general lab management (ie consumables, COSHH, EHS etc)

Scientific outreach; papers, articles, conference communication

Posted
07/09/2022
Location
Cambridgeshire, England, UK