Research Fellow in Computational Genomics, Hovestadt Lab

Research Fellow in Computational Genomics, Hovestadt Lab

Job Details

Job ID:

450 Brookline Ave, Boston, MA 02215


Employment Type:
Full time

Work Location:
Onsite:Up to 1 day remote/wk


The Hovestadt Lab in the Department of Pediatric Oncology at Dana-Farber Cancer Institute ((see application details), affiliations with Boston Children's Hospital and the Broad Institute of MIT and Harvard) is seeking a highly motivated computational postdoctoral research fellow. Our lab studies childhood brain tumors, the main cause of cancer-related death in children. We aim to better understand tumor biology using cutting-edge experimental and computational approaches. We are especially interested in studying non-genetic tumor drivers and oncogenic signaling between malignant cell populations. Translational goals of our research include development of more accurate patient classification systems and novel treatment strategies.

Interested applicants should submit a cover letter describing their personal research interests and a CV through the online submission system. Letters of support will be asked for at a later time.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.


The postdoctoral fellow will lead the computational analysis and biological interpretation of novel single-cell epigenomic datasets (incl. DNA methylation, histone modifications) generated from different types of childhood brain tumors. The goal of these analyses is to identify tumor-specific alterations relative to their respective cellular origins and to understand their role in tumor formation. The project provides ample opportunity to advance scientific skills and to collaborate with world renowned experts in the fields of childhood brain tumor research and epigenomics. Candidates need to be passionate about cancer research and intrinsically motivated. Creativity and innovative/independent thinking is a must.


  • A PhD in Cancer Biology, Epigenetics/Genetics, Computational Biology, or related discipline
  • Experience in developing computational methods to analyze and visualize new types of genomic data
  • Understanding of human developmental biology and recent single-cell profiling efforts
  • Demonstrated ability to work collaboratively with scientists from other disciplines
  • Good oral and written communication skills
  • An outstanding academic track record

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

Salary Range
$40,000.00 - 64,000.00
per Year
Salary range estimated by
Boston, MA 02298, US
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