Supervisor - In Life

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.



Perform laboratory techniques on studies of moderate complexity and exercises judgment within defined Standard Operating Procedures and practices to determine appropriate action Supervise and coordinate study related activities of research technical staff to ensure compliance with the protocol and applicable SOP’s and maintain the raw data for non-clinical studies



  • Provide direct daily supervision and review work of assigned departmental employees to ensure accuracy and to ensure adherence to pertinent departmental policies, practices, and procedures [SOPs, safety procedures and protocols.]  Schedule and prioritize workload of group members.
  • Assist in the interview and selection of qualified non-exempt personnel.  Recom­mend personnel actions, including hiring, promotions and raises.  Partner with Human Resources and depart­mental management to assist in the handling of disciplinary issues.  Draft appropriate personnel action paperwork.
  • Identify training and development needs of direct reports.  Assist in the development, implementa­tion and delivery of depart­mental training programs; ensure that direct reports receive departmental orien­tation and necessary on-the-job training.  Monitor performance of direct reports.  Provide regular coaching and counseling. 
  • Assist in preparation and delivery of salary and performance reviews of direct reports.
  • Schedule overtime as authorized.  Review and approve time cards.  Coordinate vacation/time off schedules.
  • Recommend short-range operating objectives, organizational structure of direct reports and staffing requirements.  Assist in the development of a departmental plan for backup and succession of key technical personnel.
  • Ensure optimum performance of group function.  Recommend and implement techniques to improve productivity, increase efficiencies, cut costs, take advantage of opportunities, and maintain state-of-the-art practices.
  • Assist in the development, maintenance and communication of departmental systems and SOPs.  Assist in the development and communication of job descriptions for subordinate positions.
  • Ensure that departmental equipment is maintained in good working condition and that departmental area(s) are maintained in a clean and orderly condition. 
  • Ensure raw data records are accurate, complete, and in appropriate order, and meet protocol and SOP specifications and GLP requirements.
  • Draft computer protocol requests and review document against finalized study protocol.
  • Perform rodent physical examinations, randomization and review suitability for study assignment with the Study Director.
  • Interact with Study Directors, Study Coordinators, Data Management, Animal Care and technical staff in conducting and reporting of studies.
  • Ensure routine facility husbandry is performed and documented.
  • Assume responsibilities for special projects delegated by laboratory management.
  • Confirm that the Formulations Laboratory is aware of study specific requirements.
  • Ensure that the Necropsy Laboratory is aware of study specific requirements.
  • Ensure that study samples are collected, packed and shipped properly and on time.
  • Review raw data and maintenance records as required by Standard Operating Procedures.
  • Ensure adequate supplies of all equipment/materials during the course of study.
  • Ensure that weekend laboratory assignments have been made and that the technicians assigned understand what needs to be completed and that all assignments are covered.
  • May assist in training laboratory personnel.
  • Request and review periodic summarization of data.
  • Monitor post in-life phase activities to ensure the raw data records are complete and ready for paginating and/or archiving and that the computer database for each study is accurate.
  • Assist Study Directors and Study Coordinators in preparing responses to both internal and Sponsor Quality Assurance Audits.
  • Ensure that preserved tissues and tissue packing lists are accurate and complete (sample tissue/inventory), and are archived in a timely manner.
  • Assist with facility security and emergency procedures such as setting alarms, opening or closing the building, resetting printers.
  • May assist in directing the work of laboratory personnel on weekends or holidays.
  • Perform other related duties as assigned.



  • Education:   Bachelor’s degree (B.S./B.A.) preferably in a life science, or relevant animal science education and experience.
  • Experience:   Two to four years experience in a non clinical laboratory, or a combination of non-clinical laboratory/supervisory experience.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Certification/Licensure: ALAT, LAT, or LATG preferred
  • Other:  Personal skill sets/competencies equitable with Laboratory Technician III Core Competency Matrix.



  • While performing the duties of this job, the employee is regularly required to talk, hear and type at a computer.
  • Specific vision abilities required by this job include regular use of close vision and the ability to adjust focus.
  • Required to regularly wear safety equipment and outer wear in compliance with OSHA regulations
  • Regularly record data by hand or on a computer terminal.
  • Regularly stand approximately 4 to 6 hours a day.
  • Must be able to regularly observe physical attributes of species and changes thereto.
  • Must be able to frequently firmly hold species while utilizing fine motor skills. 
  • Must be able to occasionally lift and manipulate up to 50 pounds.
  • Must be able to frequently manipulate and remove objects from shelves one and one half to six and one half feet above the floor (with the aid of a step stool).
  • Must be able to occasionally work in spaces as narrow as 2 feet.
  • Must be able to occasionally push wheeled carts weighing up to 1200 pounds.



  • General laboratory working conditions.
  • Regularly works with or near caustic chemicals and with test articles with unknown levels of toxicity. 
  • Regularly exposed to rodent dander. 
  • The noise level in the work environment is usually quiet.



 Work schedule includes weekend and all holidays on a rotating basis. 

Job Summary

Designs and/or executes scientific testing strategies and studies. Leads assay development, assay validation or study conduct, or is involved in preparation of material (e.g. protein, nucleic acid, cells, etc.). Reviews and interprets study data, communicates results to clients and writes final reports. Serves as Project Scientist, Principal Investigator, Contributing Scientist, Project Leader or Study Director, as applicable. Ensures compliance with protocols and all applicable SOPs. Troubleshoots and resolves assay or technical issues in the laboratory when scientific expertise is needed. May introduce new technologies or introduce improvements in existing technologies. Provides advisory functions to clients designing a program or experiment, dealing with specific dataset interpretation, or when appropriate answering questions from regulatory authorities.

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.


About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 13,000 employees within 80 facilities in 23 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.


At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 80% of the drugs approved by the FDA in 2017.


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Equal Employment Opportunity
Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet