CO-OP Student 1 1

The Bioengineering Systems and Technologies Group seeks to improve the performance of human-centered missions through preventing injury and disease, improving sensing and identification of people and their environment, and speeding rehabilitation and recovery. This goal is accomplished through four broad technical areas: biomedical research, synthetic biology, bioinformatics and biometrics, and forensics. Biomedical research includes advanced sensing, algorithms, modeling, prototyping, and field testing of technologies to diagnose disease, predict outcomes, avoid injuries, and monitor and enhance human performance. The synthetic biology research area emphasizes the development of tools and techniques that will greatly speed the design, evaluation, and assessment of genome-wide engineering approaches through highly integrated microfluidic devices. Bioinformatics is applied across the group to uncover signatures in high-throughput genomic, transcriptomic, and proteomic data sets. Biometrics and forensics research is developing technologies and systems for human identification, including rapid DNA analysis, standoff biometric sensing, scientific validation of forensic techniques, and integrated architecture analyses. This highly interdisciplinary group draws on skills from biology, biochemistry, biosignal processing, engineering, computer science, physics, and medical research areas. Primary government sponsors are in the Departments of Defense, Homeland Security, and Justice, as well as the National Institutes of Health.

We are seeking an undergraduate co-op to work under the direction of MIT-LL staff in performing laboratory studies aimed at developing molecular tools for in vivo engineering of the gut microbiome.  These studies will involve hands-on molecular biology and microbiology techniques for creation of new plasmids and bacterial strains, maintenance of microbial communities, bacterial conjugation/integration, and analysis of biological endpoints.  Duties will include molecular cloning (restriction digest, ligation, transformation); operation of instruments (liquid handler and plate reader); reagent preparation; and molecular, chemical, cellular, or analytical assays to generate data directed toward completion of project goals.  In addition, interns are expected to collect and record data, appropriately format data for reporting, and assist the technical staff in data interpretation. 



Completion of early course work in and basic knowledge of biology and chemistry are expected and knowledge of the principles of molecular/synthetic biology is a plus.  Experience working in a laboratory, particularly in microbiology or synthetic biology, and familiarity with general laboratory safety policies are preferred.  Also important are strong written, oral and interpersonal skills and the ability to work in a team environment. 

Candidate must be a U.S. citizen.

MIT Lincoln Laboratory
Full time