Research Scientist II (Analytical Chemistry)

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

 

 

Job Summary

We are seeking an experienced Research Scientist II (Analytical Chemistry) for our Safety Assessment site located in Shrewsbury, MA

 

The Research Scientist II (Analytical Chemistry) will design and execute Analytical Chemistry and Dose Formulation Analysis (DFA/AC) strategies and studies in support of Discovery, Pharmacology, and GLP studies at a toxicology testing facility.  Supports de novo assay development, assay transfer, assay validation, and study execution, and is involved in data review and acceptance (e.g., small molecule, protein, nucleic acid, etc.) emphasizing HPLC and UPLC expertise (reverse phase; size exclusion; ion exchange).  Familiarity with validation procedures, Empower 3, and Chemstation software and instrument maintenance and troubleshooting.  Interprets study data, communicates results to clients and internal project teams, and writes final reports.  Serves as Project Scientist, Principal Investigator, Contributing Scientist, Project Leader or Study Director, as applicable. Crafts and ensures compliance with protocols and all applicable SOPs related to DFA/AC, including partnership with site QA. Troubleshoots and resolves assays or technical issues. May introduce new technologies or introduce improvements in existing DFA/AC technologies. Provides advisory functions to clients designing a program or experiment, dealing with specific dataset interpretation, or when appropriate answering questions from regulatory authorities.  Partners with site Client Services on pricing, study design, and revenue generation, as required.  Attends and presents at scientific meetings, conferences, and training courses to advance job and professional skills.

 

The following are minimum requirements related to the Research Scientist II (Analytical Chemistry) position.

  • Education: Bachelor's degree (B.S./B.A.) or equivalent in a scientific related discipline, preferably Chemistry. Related Master's degree (M.S./M.A.) or PhD/DVM preferred.
  • Experience:  Minimum of 8 to 9 years related experience in the contract research, academic, or pharmaceutical industry. 
  • Dose formulation procedures and stability experience preferred but not required
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Certification/Licensure: Certification as appropriate for specialty preferred.
  • Other:  Understanding of regulatory requirements of study types assigned, as well as Testing Facility SOPs and the Good Laboratory Practices (GLPs), as appropriate. Demonstrate leadership skills as they pertain to intra- and interdepartmental initiatives, Sponsor interactions, and business development. Effective written and verbal communication skills. Ability to handle multiple projects, prioritize work and meet deadlines. Proficiency in the use of standard software including Microsoft® Excel, Word, Powerpoint, etc. and with standard laboratory calculations.

 

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~70% of the drugs approved by the FDA in 2016.

For more information, please visit www.criver.com.


Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet

Company
CHARLES RIVER LABORATORIES
Posted
06/22/2018
Type
Full time
Location
Shrewsbury, MA 01545, US