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Position: Research Technician, Center for Regenerative Medicine (CReM)

Location: Boston, MA

Schedule: 40 hours per week

POSITION SUMMARY:

The candidate will work closely with the Mostoslavsky lab members to support the different research projects. Primary responsibilities will include iPSCs culture for maintenance and expansion, basic characterization using PCR, cDNA preparation, Real-time PCR and immunostaining. The Research Technician will also assist with the creation of various genetically modified iPSC lines using genome-editing technologies (CRISPR/Cas9) for the study of developmental biology and disease modeling.

JOB RESPONSIBILITIES:

• Performs experiments, techniques andmolecular biological procedures (such as Western blotting, ELISA, tissue cultures, protein analysis, cloning, sequencing, isolating, etc.) according to established protocols.
• Assists with husbandry, collects samples; maintains data records. Performs animal dissections and muscle physiology experiments.
• Utilizes advanced techniques, analyzes data, and assists in designing experiments. Researches/develops alternate testing methods and techniques as required to further the research study.
• Performs audits and quality checks of data and samples. Presents weekly written report and answers questions regarding the performance of the experiments and the integrity of the data.
• Performs research literature searches as needed and assists with writing manuscripts. Assists with IRB filings and other grant-related documentation.

OTHER:

• Responsible for laboratory's chemical inventory and biohazard safety compliance. Ensure proper handling, storing and freezing of specimens and supplies, disposes of waste according to policy and ensures proper use of equipment and facilities.
• Maintains appropriate laboratory inventory and requisitions related supplies as needed.
• Provides technical supervision and guidance to students and visiting researchers. Trains new laboratory employees in safety, routine experiments, and daily laboratory operations. Ensures that all laboratory users are properly trained in standard operating procedures and equipment specific requirements. Coordinates/shares effective experimental protocols with other lab users.

JOB REQUIREMENTS

EDUCATION:

• Bachelor's degree is required.
• College level courses in biology, chemistry, molecular biology, cell biology and/or laboratory sciences are also required.

EXPERIENCE:

• At least one year of cell culture experience with excellent sterile technique is essential.
• One year experience in a laboratory setting preferred.
• Background in molecular biology and familiarity with routine laboratory tasks are highly desirable.

KNOWLEDGE AND SKILLS:

• Knowledge of safe handling procedures of hazardous materials.
• Good computer skills, including data entry and use of spreadsheet and/or database.
• Strong organizational skills and ability to prioritize tasks as dictated by the research schedule.
• Excellent interpersonal and communication skills to exchange information with Principal Investigator and other members of the laboratory.
• Knowledge of basic laboratory techniques, (e.g. pipetting, use of microbalance), serial dilutions. Previous experience with animal studies and safe handling is beneficial.
• General understanding of translational and clinical research and the federal requirements for ethical patient treatment.

This position is grant funded through 9/3/2025. There may be opportunity beyond this grant funding for position integration into ongoing operations.

JOB BENEFITS:

• Competitive pay
• Tuition reimbursement and tuition remission programs
• Highly subsidized medical, dental, and vision insurance options
• Career Advancement/Professional Development: Access a wealth of ongoing training and development opportunities that will not only enhance your skills but also expand your knowledge base especially for individuals pursuing careers in medicine or biomedical research.
• Pioneering Research: Engage in groundbreaking research projects that are driving the forefront of biomedical science.

ABOUT THE DEPARTMENT:

As the primary teaching hospital for Boston University Chobanian & Avedisian School of Medicine and BU schools of public health and dentistry, intellectual rigor shapes our inquiries. Our research is led by a belief that skin color, zip code, and financial circumstances shouldn't dictate health.

Boston Medical Center is an Equal Opportunity/Affirmative Action you need accommodation for any part of the application process because of a medical condition or disability, please send an e-mail call617-638-8582to let us know the nature of your request.

Equal Opportunity Employer/Disabled/Veterans