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A full-time position is available for a highly motivated research technician to contribute to investigating mechanisms of immune surveillance in ovarian cancer and resistance to immune and cytotoxic therapies. In particular we are using multi-omic approaches to study identify novel antigen targets in ovarian cancer, as well as advanced barcode techniques to understand therapeutic resistance in in vitro models. The laboratory uses a variety of techniques in cell culture, molecular biology, high-throughput sequencing, immunology, peptidomics, and single cell technologies to better understand how the immune system recognizes ovarian cancer. The technician will be responsible for cell and organoid culture, processing of primary human samples, basic cloning and molecular biology approaches, molecular and cellular immunology workflows including flow cytometry and immune/primary cell co-cultures. The technician should have excellent record keeping skills, and a drive to learn new technologies. Training is available in all protocols and procedures; experience with basic technique in molecular biology is strongly preferred.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Responsibilities

The candidate will be expected to independently carry out essential research functions in the laboratory that include but are not limited to experience in cell and molecular biology techniques.

Specifically, the candidate is expected to:

• contribute to a dedicated research project with supervision and mentoring from a postdoctoral fellow
• provide intellectual and interactive commitment to the position by keeping up with appropriate literature and research publications;
• design and execute standardized molecular, microbiological or biochemical experiments including the collection of information and samples from blood and tissue
• analyze experimental data and interpret results to write reports and summaries of findings including grant preparation, presentations, and co-authored publications;
• participate in formal and informal presentations of results to laboratory and staff
• participate in grant application process and manuscript preparation as required;
• collaborate well with laboratory members and broader DFCI and Boston scientific community
• maintain detailed notebooks of all work-related activities;
• monitor laboratory work to ensure compliance with Environmental Health and Safety information, as well as the standard operating procedures specific to each laboratory.
• set up, adjust, calibrate, clean, maintain and troubleshoot equipment;
• clean and maintain work areas
• order supplies necessary to conduct experiments
• be responsible for the development, modification and improvement of standard operating procedures;
• use computers, computer-interfacing equipment, robotics or high-technology applications to perform work duties

SUPERVISORY RESPONSIBILITIES:

Research Technician

No supervisory responsibilities. Normally receives detailed instructions on all work.

Qualifications

The ideal candidate should possess strong communication and organizational skills, attention to detail, and the ability to perform in a team environment. An interest in pursuing advanced education in MD, PhD, or MD-PhD programs in the future is preferred.

The position requires:

• a bachelor's degree, with a major in biology or chemistry preferred;
• previous laboratory experience, with work in molecular biology preferred;
• knowledge of information and techniques related to either biology, chemistry or medicine is preferred;
• excellent communication skills (written and verbal) and the ability to work with a wide variety of faculty and staff;
• the ability to analyze information and use logic to address work-related issues and problems;
• strong attention to detail and thorough completion of work tasks; and
• the ability to work within a team environment.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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