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Pediatrics - Critical Care

Full Time

78279BR

Job Summary

Children and young adults can develop a variety of respiratory diseases due to triggers like infections, inflammation, or lung toxicity from inhalations or medications. These respiratory diseases can manifest as trouble breathing, low oxygen, or even need for hospitalization or admission to the intensive care unit. The children most susceptible to having trouble breathing are those with complex medical conditions such as cancer, immune system problems, prematurity, or genetic syndromes. UCSF is a leader in pediatric pulmonary disorders and we are committed to improving the care of these children through scientific research.

In order to learn more about lung disease in children, we are conducting a number of translational research studies involving human biological samples collected from children treated at UCSF Benioff Children's Hospital and partner institutions. Respiratory samples are taken "from the bedside to the bench" where we analyze bulk- and single-cell DNA, RNA, and protein expression and correlate our findings with patient characteristics and outcomes. Patient samples harbor immune cells, lung cells, epithelial cells, and a vibrant microbiome that we are just beginning to explore! We aim to improve our understanding of lung diseases in children and form hypotheses that could alter our approach to diagnosis and treatment. So far we have identified previously unrecognized infectious pathogens as well as patterns of destructive inflammation in our patients that are associated with poor clinical outcomes. Our work is funded by the NIH and has been recently published in journals including Nature Medicine, Science Translational Medicine, Blood, and the American Journal of Respiratory and Critical Care Medicine.

This candidate will work in the laboratory of Dr. Matt Zinter, Assistant Professor in Pediatric Critical Care Medicine, and Dr. Joseph DeRisi, Professor of Biochemistry & Biophysics and President of the Chan Zuckerberg Biohub. The laboratory is located at the UCSF Mission Bay Campus and is adjacent to the UCSF Benioff Children's Hospital and the Chan Zuckerberg Biohub. The ideal candidate for this position will be interested in helping critically ill children and will be trained in basic laboratory techniques including an ultra-sterile approach to nucleic acid extraction, PCR, ELISA, and quantification & purification methods. Additional skills such as cell preparation and flow cytometry will be taught. Meticulous precision, technical accuracy, reliability, and a willingness to learn are of the utmost importance.

The ideal candidate will be interested in attending graduate or medical school and will benefit from being in a large vibrant laboratory group of technicians, graduate students, postdoctoral scientists, and physicians. Our team is multidisciplinary and we all learn from each other. The ideal candidate will be interested in learning about pulmonary biology and physiology and forming scientific ideas that can be tested and explored in the laboratory setting. The candidate is expected to assist with data presentations for laboratory meetings and with the generation of scientific manuscripts. Biostatistics and bioinformatics training may be very useful but are not required.

The final salary and offer components are subject to additional approvals based on UC policy.

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Please note: An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

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Department Description

The Department of Pediatrics is one of the largest and most complex departments in the School of Medicine (SOM). The department ranks 17th in the nation among Pediatric departments for funding from the National Institutes of Health (NIH). The department is comprised of 17 divisions, with clinical income form inpatient and outpatient activities totaling over $90 million dollars in charges and annual extramural funding (contracts and grants) exceeding $40 million. The Department's mission includes research (both basic and clinical), education, patient care and public service. The Department's clinical enterprise is based at the 183-bed UCSF Benioff Children's Hospital San Francisco, the 191-bed UCSF Benioff Children's Hospital Oakland, Mount Zion, Zuckerberg San Francisco General (ZSFG), and at a number of outreach clinics throughout Northern California, providing the Department with unsurpassed opportunity to meet the needs of infants, children, and young adults throughout the Bay Area. In 2019, UCSF Benioff Children's Hospitals ranked in all 10 children's specialties in U.S. News and World Report.

Required Qualifications

SRA 1:
* BA/BS in biology or chemistry or a related science and knowledge of, or experience with, the basic techniques or methods required by the position; and/or an equivalent combination of education and experience
* Willingness to work with human biological samples
* Knowledge of scientific equipment (centrifuge, pipettes, ultra-low freezers)
* Strong computer skills including the use of Microsoft Word, Excel, and Outlook
* Ability to multi-task and prioritize
* Excellent communication skills
* Flexible schedule - ability to work evenings and weekends
* Meticulous record keeping abilities

SRA II: In addition to above
* BA/BS in a related science and one or more years of recent, directly related work experience, utilizing the techniques or methods required by the position; and/or equivalent experience/training.

Preferred Qualifications

• Generally experienced in the described job duties and in the principles and practices associated with those duties with an understanding of the underlying scientific principles.
• Ability to draft routine reports and keep accurate records of work performed.
• Actively seeks opportunities to increase skills and expertise.
• Able to learn complex tasks with general instruction. Able to use experience to perform a variety of new techniques.

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009617 SRA 2 NEX

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)

Employee Class

Career

Percentage

100%

Location

Mission Bay (SF)

Shift

Days

Shift Length

8 Hours

Additional Shift Details

Monday - Friday, 8:00am - 5:00pm