Research Tech IV - Pathology

LOC_COLKET-Colket Translational Research Req ID: 72886

Shift: Days

Employment Status: Regular - Full Time 

Job Summary

RNA genomics lab at The Children's Hospital of Philadelphia and the University of Pennsylvania is seeking to appoint an experienced research assistant. The appointee will assist in running a busy experimental laboratory and will have specific responsibilities, amongst other duties, for a large number of cell line cultures and RNA extraction. The appointee will also conduct other routine molecular biology experiments, and will contribute to the development and application of new genomic/transcriptomic sequencing methodologies.

The Lin laboratory studies RNA modifications (a.k.a “epitranscriptomics”) in human diseases including cancer. Post-transcriptional RNA processing and modifications are important mechanisms for gene regulation and functional diversity in eukaryotic cells. We develop and apply high-throughput sequencing strategies and transcriptome engineering technologies to study the regulation and function of RNA modifications including A-to-I RNA editing and m6A RNA methylation.

The ideal candidate will

  Assist in running a busy experimental laboratory, including maintaining a large number of mammalian cell cultures, carrying out molecular assays, keep clear experimental record according to specific format.

  Communicate complex ideas and concepts to those with limited knowledge and understanding as well as to peers.

  Mentor and coach colleagues with less experience

  Undergraduate degree in biology, biotechnology or a related discipline, at a leading academic institution.

  Specific research expertise in one or more of the following topics is preferred: RNA biology, molecular biology, genomics, cancer biology, next-gen sequencing.

  Experience working with RNA, mammalian cell culture, molecular cloning.

Job Responsibilities
  • Independently performs advanced, complex research procedures on experimental samples
  • Formulates and performs complex lab experiments and analyzes reports the data including interpretation of methodologies
  • Performs advanced calculations and maintains appropriate log and lab notebooks
  • Plans and modifies research protocols and procedures with minimal direction from the principal investigator or supervisor
  • Assists in development & troubleshooting of new techniques and ideas
  • Prepares laboratory reagents, monitors and maintains laboratory inventory
  • Supervises, trains and mentors junior and new staff members
  • Determines work assignments, schedules and laboratory priorities
  • Presents & discusses work at weekly lab meetings and national symposia
  • Assists in writing of grants, journal articles, poster and oral presentations
Required Education and Experience

Required Education: Bachelor’s Degree


Required Experience: Two (2) years of laboratory experience

Preferred Education, Experience & Cert/Lic

Preferred Education: Bachelor’s Degree


Preferred Experience:

  • Three (3) years of laboratory experience
  • Previous supervisory experience.

All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products.

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

VEVRAA Federal Contractor/Seeking priority referrals for protected veterans.  Please contact our hiring official with any referrals or questions.

CHOP Careers Contact 

Talent Acquisition

2716 South Street, 6th Floor

Philadelphia, PA 19146 



Salary Range
$39,000.00 - 58,000.00
per Year
Salary range estimated by
Philadelphia, PA 19104, US