Chromatography Technician II

For nearly 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.


We are seeking a Process Development Research Associate II for our Biologics Testing Solutions site located in King of Prussia, PA. 

  • Perform routine experiments, tests and procedures, such as:
    • Perform end-point laboratory assay and evaluations (TCID50, Plaque assay, qPCR tests)
    • Perform or participate in wide variety of complex client processes to support Viral Clearance studies
    • Work with cell cultures and virus stocks
  • Execute chromatography processes related to client studies.
  • Assist in the guidance of less experienced technicians.  Assist in determining daily work flow.
  • Prepare materials and buffers used in projects.
  • Make detailed observations and accurately and precisely record data. Summarize data for reports.  Perform simple graphic analysis of data.
  • Practice proper aseptic and sterile processes.
  • Perform calibration, monitoring and cleaning of laboratory and lab equipment when deemed necessary by department management.
  • Maintain inventory of necessary supplies by ordering and / or preparing reagents, media and solutions.
  • Assist with method qualifications and validations as required.
  • Efficiently organize and plan daily activities.
  • Maintain a safe working environment by adhering to company policies and procedures.
  • Follow all protocols, SOPs, and regulations as they relate to specific tasks.


The following are minimum requirements related to the Process Development Research Associate II position.


  • Education: Bachelor’s degree (B.A. / B.S.) or equivalent in Biology or related discipline.  Related Master's Degree (M.A. / M.S.) preferred.
  • Experience: 3-5 years related experience in industry, area or discipline. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed herein.
  • Certification / Licensure: None
  • Other: Experience in a GLP or GMP laboratory is preferred.  Must have experience with aseptic technique.  Must be able to perform basic math functions. Able to communicate effectively in group settings. Basic Microsoft Office skills are required.


About Biologics Testing Solutions
With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs.  Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015. At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~70% of the drugs approved by the FDA in 2016

For more information, please visit

Equal Employment Opportunity
Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet


Full time
King of Prussia, Pennsylvania 19406, US